产品货号：
Z32112
中文名称：
CLOCK抗体
英文名称：
Anti-CLOCK Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CLOCK Antibody |
| 指标别名 | bHLHe8;CLOCK;clock homolog (mouse);hCLOCK;KAT13D;KIAA0334 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | CLOCK |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human CLOCK Circadian rhythms govern many key physiological processes that fluctuate with a period of approximately 24hours.These processes include the sleep-wake cycle,glucose,lipid and drug metabolism,heart rate,hormone secretion,renal blood flow,and body temperature,as well as basic cellular processes such as DNA repair and the timing of the cell division cycle. |
| 实际分子量 | 95KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Clock (Circadian Locomotor Output Cycles Kaput) is also known as KAT13D.The protein encoded by this gene plays a central role in the regulation of circadian rhythms.This protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity.And the encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1,PER2,PER3) and Cryptochrome (CRY1,CRY2) genes and activates transcription of these genes.PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes.Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome.Alternative splicing results in multiple transcript variants. |
| Uniprot ID | O15516 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 Flow cytometry (FCM) 1:20 |
相关搜索：CLOCK抗体，CLOCK单抗，Anti-CLOCK Antibody